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Thermo Fisher
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Thermo Fisher
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Journal: Cancers
Article Title: Aberrant Expression of BTLA , CD160 , SPN , TIM-3 , VISTA and TIGIT in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers
doi: 10.3390/cancers17132116
Figure Lengend Snippet: The aberrant expression of BTLA , CD160 , SPN , TIM3 , VISTA , TIGIT in CLL and psoriatic patients compared to HVs. ( a ) Higher expression of BTLA in in CLL patients, as well as Ps patients, compared to HVs (1500 vs. 5.372, p < 0.0001), (18.22 vs. 5.372, p < 0.0001). Higher expression of BTLA in CLL patients than psoriatic patients (1500 vs. 18.22, p < 0.0001). ( b ) Higher expression of CD160 in CLL patients than HVs (86.94 vs. 11.96, p < 0.0001). Higher expression of CD160 in psoriatic patients than HVs (48.92 vs. 11.96, p < 0.0001). Higher expression of CD160 in CLL than Ps patients (86.94 vs. 48.92, p = 0.0243). ( c ) Higher expression of SPN in CLL patients than HVs (1706 vs. 82.24, p < 0.0001). Higher expression of SPN in psoriatic patients than HVs (451.8 vs. 82.24, p < 0.0001). Higher expression of SPN expression in CLL patients than Ps patients (1706 vs. 451.8, p < 0.0001). ( d ) Lower expression of TIM-3 in Ps patients than HVs (0.02485 vs. 183.1, p < 0.0001). Higher expression of TIM-3 in CLL than Ps patients (226.9 vs. 0.02485, p < 0.0001). No difference in TIM-3 expression in CLL patients than HVs (226.9 vs. 183.1, p = 0.7251). ( e ) Higher expression of VISTA in Ps patients than HVs (196.7 vs. 34.93, p < 0.0001). Higher expression of VISTA in Ps patients compared to CLL patients (196.7 vs. 27.50, p < 0.0001). No difference in VISTA expression in CLL patients than HVs (27.50 vs. 34.93, p = 0.1854). ( f ) Higher expression of TIGIT in CLL patients than Ps patients (409.6 vs. 109.9, p < 0.0001). Higher expression of TIGIT in CLL patients than HVs (409.6 vs. 19.41, p < 0.0001). Higher expression of TIGIT in Ps patients than HVs (109.9 vs. 19.41, p < 0.0001). The bars spans from Q1 to Q3, and represents the interquartile range (IQR); a line marks the median.
Article Snippet: cDNA was used in a qRT-PCR to measure the mRNA expression of BTLA (Hs00699198_m1), CD160 (
Techniques: Expressing
Journal: Cancers
Article Title: Aberrant Expression of BTLA , CD160 , SPN , TIM-3 , VISTA and TIGIT in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers
doi: 10.3390/cancers17132116
Figure Lengend Snippet: Positive correlations between expression of BTLA , CD160 , SPN , TIM3 , VISTA , and TIGIT in CLL. The results are presented as the log10 value of 2 −∆∆Ct , with the regression line marked. ( a ) Strong correlation between the expressions of SPN and CD160 (r = 0.7822, p < 0.0001). ( b ) Strong correlation between the expressions of SPN and BTLA (r = 0.7960, p < 0.0001). ( c ) Moderate correlation between the expressions of SPN and TIGIT (r = 0.6800, p < 0.0001). ( d ) Moderate correlation between the expressions of CD160 and TIM3 (r = 0.6212, p < 0.0001). ( e ) Moderate correlation between the expressions of BTLA and TIGIT (r = 0.6774, p < 0.0001). ( f ) Moderate correlation between the expressions of TIM3 and VISTA (r = 0.6331, p < 0.0001).
Article Snippet: cDNA was used in a qRT-PCR to measure the mRNA expression of BTLA (Hs00699198_m1), CD160 (
Techniques: Expressing
Journal: Cancers
Article Title: Aberrant Expression of BTLA , CD160 , SPN , TIM-3 , VISTA and TIGIT in Chronic Lymphocytic Leukemia and Psoriasis Patients Compared to Healthy Volunteers
doi: 10.3390/cancers17132116
Figure Lengend Snippet: Positive correlations between expression of BTLA , CD160 , SPN , TIM3 , VISTA , TIGIT in Ps. The results are presented as the log10 value of 2 −∆∆Ct , with the regression line marked. ( a ) Strong correlation between the expressions of SPN and TIGIT (r = 0.8246, p < 0.0001). ( b ) Moderate correlation between the expressions of SPN and TIM3 (r = 0.6572, p < 0.0001). ( c ) Strong correlation between the expressions of SPN and BTLA (r = 0.7016, p < 0.0001). ( d ) Strong correlation between the expressions of SPN and CD160 (r = 0.7183, p < 0.0001). ( e ) Moderate correlation between the expressions of CD160 and TIM3 (r = 0.6263, p < 0.0001). ( f ) Strong correlation between the expressions of CD160 and TIGIT (r = 0.7576, p < 0.0001).
Article Snippet: cDNA was used in a qRT-PCR to measure the mRNA expression of BTLA (Hs00699198_m1), CD160 (
Techniques: Expressing